Medical & Healthcare

IRELEC designs and manufactures a line of automated systems for the storage and retrieval of biological samples kept in nitrogen tanks.

Storage in nitrogen tanks is a tried and tested method for long-term storage of biological samples.

When performed manually, the operations to add and retrieve samples constitute a serious weakness of this storage method due to the risks involved in terms of arduousness, personnel safety and sample quality alteration as a result of the samples heating up.

Thanks to their innovative design, the IRELEC Automated Biobank Management systems protect personnel and preserve the cold chain for all samples during these critical and recurrent operations.

IRELEC's automated systems are the only systems capable of adapting to existing biobank tanks.

Completely separable, they are modular and adapt to biobanks of any size.

These systems are very ergonomic and offer numerous possibilities (carrying out important operations without requiring the presence of personnel, inventories, etc.).

The Grenoble University Hospital biobank was delivered an automated system from IRELEC in March 2017.

PMB designs, develops and manufactures the FlashKnife radiotherapy system which delivers an ultra-high dose rate in a fraction of a second, sparing healthy tissue while effectively destroying cancer cells. The efficacy of FLASH has been shown in several preclinical studies, reproducibly, as compared to the damage caused by conventional radiotherapy.

This very short irradiation time eliminates any effect of organ or tumor movement and greatly enhances targeting precision and accuracy.

PMB designs, develops and manufactures iMiGiNE, an automated radioactive tracer production system.

iMiGINE is a combination of the ISOTRACE superconducting cyclotron and the iMiLab innovative radiochemistry room, all of this assisted by a strict quality control system. Fully automated and robotized, iMiGiNE enables production by dose of a wide variety of injectable radiopharmaceuticals. A limited number of staff is needed for operation and its footprint is minimal.

This unique product is a game changer: enabling the production of radiopharmaceuticals within imaging and research centres. iMiGiNE breaks away from the traditional centralized radioactive tracer production process, which is complicated and having limited results.

This system provides exciting new possibilities in the fields of molecular imaging and research in nuclear medicine. 

PMB designs and manufactures the iMiLab system, an integral part of the complete iMiGiNE system.

iMiLab is a fully-automated radiochemistry room that produces various radioactive tracers based in particular on radio-isotopes ¹⁸F, ¹¹C and ⁶⁸Ga. iMiLab is ultra-compact, self-shielded and complies with Good Manufacturing Practices (GMP).

iMiLab uses microfluidic techniques to produce various radioactive tracers in automatic synthesis boxes and in sterile cartridges, with precursors and solvents incorporated in the system. This system enables different radioactive tracers to be produced in the same day without risk of cross-contamination.

PMB designs, develops and manufactures the iMiTRACE cyclotron, specifically designed for the in situ production of injectable radiopharmaceuticals for humans in PET (Positron Emission Tomography) imaging centers.

Its main characteristics are its compactness/lightness, its proton acceleration capacity to an energy of 12 MeV, its self-shielding feature, its superconductive magnet and its 4-port targetry.

The unique design of the iMiTRACE cyclotron guarantees great stability and availability in production. It is the result of the technological developments made to the OSCAR cyclotron (Oxford Instruments), with 20 years of proven reliability.

PMB designs, develops and manufactures a line of S band linear particle accelerators (LINAC ORIATRON), with energies of 3, 4, 6 and 7 MeV.

The PMB teams also carry out maintenance of these machines, guaranteeing quick service and maximum machine availability.

The LINAC ORIATRON has a focal spot reduced to 0.6 mm giving a higher dose rate. It has numerous possible options, helping it to meet the specific requirements of each project. 

EDIT-B is a first-in-class, clinically validated, CE marked blood test with excellent sensitivity and specificity for the differential diagnosis of bipolar disorder and depression.

The objective is to drastically reduce the diagnostic delay for bipolar disorder, which is today over seven years, and by doing so, to contribute to an optimized patients’ management for a better quality of life. EDIT-B aims to answer a major diagnostic unmet need with its unique technology based on the study of RNA and Artificial Intelligence.

EDIT-B is intended for adult patients treated for depression symptoms, as a decision-making support tool for mental healthcare providers.

ALCEDIAG is the maker of EDITOX, a cellular test evaluating the risk of a molecule of causing psychiatric side effects in humans, in particular depression and suicide.

EDITOX is primarily intended for use by pharmaceutical companies during preclinical development phases to anticipate the potential psychiatric side effects in a drug candidate.

EDITOX is an effective, economically advantageous and ethical alternative to the tests currently conducted on rodents.

Sensitivity: 88% - Specificity: 99% (validated by a clinical study) 

SkillCell and Sys2Diag/CNRS have developed the EasyCOV saliva-based test dedicated to the fight against the Covid-19 pandemic.

Very easy to use, painless, highly reliable, requiring no interaction with a medical laboratory, EasyCOV delivers a result in 40 minutes through a visual interpretation of color change. 

Designed and manufactured in France, EasyCOV is a Covid-19 screening solution that is efficient and economical.

SkillCell has developed IDIR^® (IDentification of Insulin Resistance), the first urine test to diagnose insulin resistance. Supported by a clinical study, IDIR® addresses the issue of overweight/obesity and metabolic disorders such as T2 Diabetes, major challenges in public health with very significant socio-economic implications.

IDIR®’s main indications: 

• T2 Diabetes prevention

SkillCell develops rapid and smart tests for health, food and the environment. The company's first products, currently under development, are:

• A urine test to screen for insulin resistance
• A test to detect pesticides, in particular in food
• A test to detect mosquito eggs/larvae in watering places

BETA BEAMS provides electron accelerators (50 keV to 800 keV) for surface and core sterilization and has developed an e-beam sterilization equipment using Pulse power technology. This innovative system consists of delivering a large quantity of electrons in an extremely short time, in the nanosecond range, in order to achieve very high instantaneous dose rates. This cost-effective technology requires no use of chemical products (EtO, H2O2) and can be an alternative to batch or gamma equipment.

BETA BEAMS is a trademark of ITOPP.

PMB designs and manufactures a variety of HF components in-house: accelerating sections, electron guns, HF windows, ionization chambers, gun filaments, etc.